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Dr Marvin E Klein is the inventor of AFAs, he is also the inventor of esterified glycolics and the TCA Masque. Dr Klein is a respected dermatologist with over 35 years of experience, he is a Fellow and Life Member of the American Academy of Dermatology.
The letters AFA stand for Amino acid Filaggrin based Antioxidants. Filaggrin, a protein that occurs in the upper layer of the skin is composed of acidic amino acids which are the primary agents responsible for the skins ability to retain moisture. AFAs are made up of these same acidic amino acids and thus promote active moisture retention.
AFAs are very effective exfoliants, this is because they combine a low pH with a small molecular size. The pH of our gels is below 2.0 and the molecular weight of AFAs is under 100. This is a small enough molecule to penetrate fully into the skin and a low enough pH to be an effective kerolytic.
The AFA molecular structure contains 3 positively charged hydrogen ions, one in each of 3 carboxyl groups, these are widely believed to be responsible for the potent antioxidant effect of AFAs. Compare this to AHAs which have one positively charged hydrogen ion i.e. they have one carboxyl group.
In independent studies patients have often noticed an improvement in their skin within the first few days to a week of using the AFA Gels! This is likely due to the immediate increase in moisture retention of the skin.
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AFAs are non-allergenic, non-comedogenic, non-photosensitising & are not tested on animals. US Patent No. 6197317
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